Theme: Recent Advancement in Mass Spectrometry

LCMS-2016
Past Report of Mass Spectrometry-2015

LCMS-2016

Track 1: New approaches in mass spectrometry

The search of metabolites which are present in biological samples and the comparison between different samples allow the construction of certain biochemical patterns. The mass spectrometry (MS) methodology applied to the analysis of biological samples makes it possible for the identification of many metabolites. The 100 chromatograms were concatenated in a vector. This vector, which can be plotted as a continuous (2D pseudospectrum), greatly simplifies for one to understand the subsequent dimensional multivariate analysis. To validate the method, samples from two human embryos culture medium were analyzed by high-pressure liquid chromatography-mass spectrometry (HPLC–MS). They work on the principle that many microorganisms have their own unique mass spectral signature based on the particular proteins and peptides that are present in the cells.

Identification of unknown peaks in gas chromatography (GC/MS)-based discovery metabolomics is challenging, and remains necessary to permit discovery of novel or unexpected metabolites that may allergic diseases  processes and/or further our understanding of how genotypes relate to phenotypes. Here, we introduce two new technologies and an advances in pharmaceutical analytical methods that can facilitate the identification of unknown peaks. First, we report on a GC/Quadrupole-Orbitrap mass spectrometer that provides high mass accuracy, high resolution, and high sensitivity analyte detection.

Related conferences of new approaches in mass spectrometry

2nd International Conference on Current Trends in Mass Spectrometry May 09-11, 2016 Chicago, USA; International Conference and Exhibition on Advances in HPLC and Chromatography Techniques, March 17-18, 2016, London, UK; International Conference on Pharmaceutical Chemistry August 04-06, 2016, Frankfurt, Germany; 4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing, November 02-04, 2015 Atlanta, USA;  2nd International Conference and Expo on Separation Techniques, November 03-05, 2016, Valencia, Spain; Asia Pacific Drug Formulation & Bioavailability Congress June 06-08, 2016, Beijing, China; Global Pharmaceutical Industry Summit September 19-21, 2016, Vienna, Austria; 5th International Conference on Forensic Research & Technology November 17-19, 2016;  International Pharmacy Conference July 11-12, 2016, Philadelphia, USA ;  2nd International Conference on Therapeutic Drug Monitoring and Toxicogenomics, June 09-10, 2016, Dallas, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy

Spectroscopy in Pharmaceutical Bioprocessing April 15-20, 2016, Island, Croatia ; 21st International Mass Spectrometry Conference  August 20-26, 2016, Toronto, Canada;  BMSS Course: Introduction to  Mass Spectrometry, September 12-13, 2016, Eastbourne, England ; MSACL, US-8th Annual conference  & exhibits in Mass spectrometry , February 21-25, 2016, Palm springs, California ; Mass Spectrometry Congress November 14 - 15, 2016, London, UK ;  18th International Conference on Clinical Mass Spectrometry October 27-28, 2016, London UK ; Mass Spectrometry: Applications to the Clinical Laboratory, February 21-25, 2016, California, USA;  64th  ASMS  Conference in Mass spectrometry ,  June 05-09,2016; San Antonio, USA;  Pittcon conference and expo on analytical chemistry and applied spectroscopy , March 6-10, 2016, Atlanta, USA;  International Summit On Current Trends in Mass Spectrometry, May 09-11, 2016, Chicago, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy,American Society for Mass Spectrometry (ASMS)Belgian Society for Mass Spectrometry  (BSMS), Brazilian Mass Spectrometry Society (BrMASS)

Track 2:  Experimentation tools in mass spectrometry

Mass spectrometric analysis of biological samples has increasingly entailed direct analysis of complex protein mixtures, often with the objective of detailed characterization of the various components. This trend toward ever greater sample complexity has been enabled and in turn driven by the rapid development of powerful mass spectrometric tools. A general characteristic of recent mass spectrometers is that most are composed of a sequence of multiple mass analyzers with different strengths and properties, resulting in tandem instruments that possess capabilities unattainable by the individual components .can combine high mass accuracy with high-speed measurement, greatly facilitating the analysis of complex mixtures. This option is advantageous when speed and accuracy are crucial for the success of analysis, as it is, for example, when the mass spectrometer is coupled on-line to an HPLC system .Physical coupling of multiple mass spectrometers in tandem mass spectrometry has some disadvantages. Optimal operation conditions for different mass spectrometers and modes of operation of a tandem instrument may differ significantly, producing the need to compromise in the performance of one mass spectrometer at the expense of another  Decoupling the parts of a hybrid instrument is one solution to this problem.

The collected data can be analyzed quickly by a computer, which generates a set of instructions based on the results of analysis of the data obtained in the previous instrument and passes them to the next one. Theoretical speed of the analysis in such a modular tool is only limited by the speed of the sample analysis in the different instruments and the speed of transfer of the remaining part of the sample from one mass spectrometer to another. This concept has been used to combine a high resolution, high mass accuracy MALDI-QTOF instrument with a high-speed, high-sensitivity MALDI-IT   mass spectrometer. This combination has proven to be extremely useful for gaining insight into many challenging biological problems   Initial studies of the utility of this instrument combination utilized in-house modified instruments. However, the recent commercial introduction of similar mass spectrometers has opened the possibility to reproduce this approach in any laboratory.

Related conferences of experimentation tools mass spectrometry:

International Conference and Exhibition on Advances in HPLC and Chromatography Techniques March 17-18, 2016, London, UK; 2nd International Conference on Current Trends in Mass Spectrometry May 09-11, 2016 Chicago, USA; International Conference on Pharmaceutical Chemistry August 04-06, 2016, Frankfurt, Germany; 4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing November 02-04, 2015, Atlanta, USA;  2nd International Conference and Expo on Separation Techniques November 03-05, 2016 Valencia,7th Annual Global Pharma Summit June 20-22, 2016, New Orleans, USA; 2nd International Conference and Expo on Bio pharmaceutics September 15-17, 2016, San Antonio, USA; Pharma Middle East November 02-04, 2015 Dubai, UAE;  8th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems March 07-09, 2016, Madrid, Spain; African Pharma Congress June 20-22, 2016, Cape Town, South Africa; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy

64th  ASMS  Conference in Mass spectrometry, June 05-09, 2016; San Antonio, USA; Pittcon conference and expo on analytical chemistry and applied spectroscopy , March 6-10, 2016, Atlanta, USA; 21st International Mass Spectrometry Conference, August 20-26, 2016, Toronto, Canada;  BMSS Course: Introduction to  Mass Spectrometry, September 12 -13 , 2016, Eastbourne, England; International Summit on Current Trends in Mass Spectrometry May 09-11, 2016, Chicago, USA; Spectroscopy in Pharmaceutical Bioprocessing, April 15-20, 2016, Island, Croatia; MSACL, US-8th Annual conference  & exhibits in Mass spectrometry February 21 - 25, 2016, Palm springs, California; Mass Spectrometry Congress November 14-15, 2016, London; 18th International Conference on Clinical Mass Spectrometry October 27-28, 2016, London UK; Mass Spectrometry: Applications to the Clinical Laboratory, February 21-25, 2016, California, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy,Canadian Society for Mass Spectrometry (CSMS)Danish Society for Mass Spectrometry (DSM)European Society for Mass Spectrometry (ESMS)

Track 3: Analytical methods 

An analytical technique is a method that is used to determine the concentration of a chemical compound or chemical element. There are a wide variety of techniques used for analysis, from simple weighing (gravimetric analysis) to titrations (titrimetric) to very advanced techniques using highly specialized instrumentation. The most common techniques used in analytical chemistry are the following:

·         Titrimetry, based on the quantity of reagent needed to react with the analyte

·         Electro analytical methods, including  potentiometry and voltammetry;

·         Spectroscopy, based on the differential interaction of the analyte along with electromagnetic radiation;

·         Chromatography, in which the analyte is separated from the rest of the sample so that it may be measured without interference from other compounds;

·         Gravimetric analysis

·         Microscopy

·         Radio analytical chemistry

There are many more techniques that have specialized applications, and within each major analytical technique there are many applications and variations of the general techniques.

Related conferences of analytical methods:

International Conference and Exhibition on Advances in HPLC and Chromatography Techniques March 17-18, 2016, London, UK; 2nd International Conference on Current Trends in Mass Spectrometry May 09-11, 2016 Chicago, USA; International Conference on Pharmaceutical Chemistry August 04-06, 2016, Frankfurt, Germany; 4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing November 02-04, 2015, Atlanta, USA;  2nd International Conference and Expo on Separation Techniques November 03-05, 2016 Valencia,7th Annual Global Pharma Summit June 20-22, 2016, New Orleans, USA; 2nd International Conference and Expo on Bio pharmaceutics September 15-17, 2016, San Antonio, USA; Pharma Middle East November 02-04, 2015 Dubai, UAE;  8th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems March 07-09, 2016, Madrid, Spain; African Pharma Congress June 20-22, 2016, Cape Town, South Africa; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy

64th  ASMS  Conference in Mass spectrometry, June 05-09, 2016; San Antonio, USA; Pittcon conference and expo on analytical chemistry and applied spectroscopy , March 6-10, 2016, Atlanta, USA; 21st International Mass Spectrometry Conference, August 20-26, 2016, Toronto, Canada;  BMSS Course: Introduction to  Mass Spectrometry, September 12 -13 , 2016, Eastbourne, England; International Summit on Current Trends in Mass Spectrometry May 09-11, 2016, Chicago, USA; Spectroscopy in Pharmaceutical Bioprocessing, April 15-20, 2016, Island, Croatia; MSACL, US-8th Annual conference  & exhibits in Mass spectrometry February 21 - 25, 2016, Palm springs, California; Mass Spectrometry Congress November 14-15, 2016, London; 18th International Conference on Clinical Mass Spectrometry October 27-28, 2016, London UK; Mass Spectrometry: Applications to the Clinical Laboratory, February 21-25, 2016, California, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy, Finnish Mass Spectrometry Society (FMSS) ,Norwegian Society for Mass Spectrometry (NSMS),Polish Mass Spectrometry Society (PTSM)

Track 4: Mass spectrometry imaging :

Mass spectrometry imaging is a technique used in mass spectrometry to visualize the spatial distribution of chemical compositions e.g. compounds, biomarker, metabolites, peptides or proteins by their molecular masses. Although widely used traditional methodologies like radiochemistry and immunohistochemistry achieve the same goal as MSI, they are limited in their abilities to analyze multiple samples at once, and can prove to be lacking if researchers do not have prior knowledge of the samples being studied. Emergency Radiology in the field of MSI are MALDI imaging and secondary ion mass spectrometry imaging (SIMS imaging). Imaging Mass Spectrometry is a technology that combines advanced analytical techniques for the analysis of biomedical Chromatography with spatial fidelity. An effective approach for imaging biological specimens in this way utilizes Matrix-Assisted Laser Desorption Ionization Mass Spectrometry (MALDI MS). Briefly, molecules of interest are embedded in an organic matrix compound that assists in the desorption and ionization of compounds on irradiation with a UV laser. The mass-to-charge ratio of the ions are measured using a Tandem Mass Spectrometry over an ordered array of ablated spots. Multiple analytes are measured simultaneously, capturing a representation or profile of the biological state of the molecules in that sample at a specific location on the tissue surface.

Related conferences of mass spectrometry imaging:

4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing November 02-04, 2015, Atlanta, USA; International Conference and Exhibition on Advances in HPLC and Chromatography Techniques March 17-18, 2016 London, UK; 2nd International Conference on Current Trends in Mass Spectrometry May 09-11, 2016 Chicago, USA;; International Conference on Pharmaceutical Chemistry August 04-06, 2016 Frankfurt, Germany; 2nd International Conference and Expo on Separation Techniques November 03-05, 2016,Valencia, Spain; 2nd International Conference and Expo on Drug Discovery & Designing November 07-09, 2016 Istanbul, Turkey; 7th Annual Global Pharma Summit June 20-22, 2016 New Orleans, USA; 9th World Drug Delivery Summit June 30-July 02, 2016 New Orleans, USA; 8th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems March 07-09, 2016 Madrid, Spain; 2nd International Conference on Therapeutic Drug Monitoring and Toxicogenomics, June 09-10, 2016 Dallas, USA;Chemistry Conferences Europe June 16-18, 2016 Rome, Italy

 

64th ASMS Conference in Mass spectrometry , June 05-09, 2016; San Antonio, USA 21st International Mass Spectrometry Conference, August 20-26 , 2016, Toronto, Canada; MSACL, US-8th Annual conference  & exhibits in Mass spectrometry February 21-25, 2016, Palm springs, California; BMSS Course: Introduction to  Mass Spectrometry, September 12-13, 2016, Eastbourne, England; 18th International Conference on Clinical Mass Spectrometry October 27-28, 2016, London, UK;  Mass Spectrometry: Applications to the Clinical Laboratory, February21-25, 2016, California, USA Mass Spectrometry Congress November 14-15, 2016, London, UK; Pittcon conference and expo on analytical chemistry and applied spectroscopy , March 6-10, 2016, Atlanta, USA , International Summit on Current Trends in Mass Spectrometry May 09-11, 2016 ,Chicago, USA;  Spectroscopy in Pharmaceutical Bioprocessing, April 15-20, 2016 , Island, Croatia; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy,Spanish Society for Mass Spectrometry (SEEM),Taiwan Society for Mass Spectrometry (TSMS)Norwegian Society for Mass Spectrometry (NSMS)

Track 5:Recent advances in mass spectrometry

New mass spectrometry (MS) methods, collectively known as data independent analysis and hyper reaction monitoring, have recently emerged. The analysis of peptides generated by proteolytic digestion of proteins, known as bottom-up proteomics, serves as the basis for many of the protein research undertaken by mass spectrometry (MS) laboratories. Discovery-based or shotgun proteomics employs data-dependent acquisition (DDA). Herein, a hybrid mass spectrometer first performs a survey scan, from which the peptide ions with the intensity above a predefined threshold value, are stochastically selected, isolated and sequenced by product ion scanning. n targeted proteomics, selected environmental Monitoring (ERM), also known as multiple reaction monitoring (MRM), is used to monitor a number of selected precursor-fragment transitions of the targeted amino acids. The selection of the SRM transitions is normally calculated on the basis of the data acquired previously by product ion scanning, repository data in the public databases or based on a series of empirical rules predicting the Enzyme structure sites

Related conferences of recent advances in mass spectrometry:

2nd International Conference on Current Trends in Mass Spectrometry May 09-11, 2016 Chicago, USA; International Conference and Exhibition on Advances in HPLC and Chromatography Techniques, March 17-18, 2016, London, UK; International Conference on Pharmaceutical Chemistry August 04-06, 2016, Frankfurt, Germany; 4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing, November 02-04, 2015 Atlanta, USA;  2nd International Conference and Expo on Separation Techniques, November 03-05, 2016, Valencia, Spain; Asia Pacific Drug Formulation & Bioavailability Congress June 06-08, 2016, Beijing, China; Global Pharmaceutical Industry Summit September 19-21, 2016, Vienna, Austria; 5th International Conference on Forensic Research & Technology November 17-19, 2016;  International Pharmacy Conference July 11-12, 2016, Philadelphia, USA ;  2nd International Conference on Therapeutic Drug Monitoring and Toxicogenomics, June 09-10, 2016, Dallas, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy

Spectroscopy in Pharmaceutical Bioprocessing April 15-20, 2016, Island, Croatia ; 21st International Mass Spectrometry Conference  August 20-26, 2016, Toronto, Canada;  BMSS Course: Introduction to  Mass Spectrometry, September 12-13, 2016, Eastbourne, England ; MSACL, US-8th Annual conference  & exhibits in Mass spectrometry , February 21-25, 2016, Palm springs, California ; Mass Spectrometry Congress November 14 - 15, 2016, London, UK ;  18th International Conference on Clinical Mass Spectrometry October 27-28, 2016, London UK ; Mass Spectrometry: Applications to the Clinical Laboratory, February 21-25, 2016, California, USA;  64th  ASMS  Conference in Mass spectrometry ,  June 05-09,2016; San Antonio, USA;  Pittcon conference and expo on analytical chemistry and applied spectroscopy , March 6-10, 2016, Atlanta, USA;  International Summit On Current Trends in Mass Spectrometry, May 09-11, 2016, Chicago, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy,Danish Society for Mass Spectrometry (DSM),British Mass Spectrometry Society (BMSS),Norwegian Society for Mass Spectrometry (NSMS)

Track 6: Fundamentals of mass spectrometry

As per Fundamentals of Mass Spectrometry, Mass spectrometry is an analytical tool used for measuring the molecular mass of a sample. Ionization is the atom or molecule is ionized by knocking one or more electrons off to give a positive ion. This is true even for things which you would normally expect to form negative ions or never form ions at all. Most mass spectrometers work with positive ions. New Ion activation methods for tandem mass spectrometry; this is followed by tandem mass spectrometry, which implies that the activation of ions is distinct from the laboratory research, and that the precursor and product ions are both characterized independently by their mass/charge ratios. As per the Frost and Sullivan report pharmaceutical analytical market is growing on an average 0.4% annually. This report studies the global mass spectrometry market over the forecast period of 2013 to 2018. Once analyte ions are formed in the gas phase, a variety of mass analyzers are available and used to separate the ions according to their mass-to-charge ratio (m/z). Mass spectrometers operate with the dynamics of charged particles in electric and magnetic particles in vacuum described by the Lorentz force law and Newton’s second law of motion.

Related conferences of fundamentals of mass spectrometry:

7International Conference and Exhibition on Advances in HPLC and Chromatography Techniques March 17-18, 2016, London, UK; 2nd International Conference on Current Trends in Mass Spectrometry May 09-11, 2016 Chicago, USA; International Conference on Pharmaceutical Chemistry August 04-06, 2016, Frankfurt, Germany; 4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing November 02-04, 2015, Atlanta, USA;  2nd International Conference and Expo on Separation Techniques November 03-05, 2016 Valencia,7th Annual Global Pharma Summit June 20-22, 2016, New Orleans, USA; 2nd International Conference and Expo on Bio pharmaceutics September 15-17, 2016, San Antonio, USA; Pharma Middle East November 02-04, 2015 Dubai, UAE;  8th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems March 07-09, 2016, Madrid, Spain; African Pharma Congress June 20-22, 2016, Cape Town, South Africa; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy

64th  ASMS  Conference in Mass spectrometry, June 05-09, 2016; San Antonio, USA; Pittcon conference and expo on analytical chemistry and applied spectroscopy , March 6-10, 2016, Atlanta, USA; 21st International Mass Spectrometry Conference, August 20-26, 2016, Toronto, Canada;  BMSS Course: Introduction to  Mass Spectrometry, September 12 -13 , 2016, Eastbourne, England; International Summit on Current Trends in Mass Spectrometry May 09-11, 2016, Chicago, USA; Spectroscopy in Pharmaceutical Bioprocessing, April 15-20, 2016, Island, Croatia; MSACL, US-8th Annual conference  & exhibits in Mass spectrometry February 21 - 25, 2016, Palm springs, California; Mass Spectrometry Congress November 14-15, 2016, London; 18th International Conference on Clinical Mass Spectrometry October 27-28, 2016, London UK; Mass Spectrometry: Applications to the Clinical Laboratory, February 21-25, 2016, California, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy,American Society for Mass Spectrometry (ASMS)Belgian Society for Mass Spectrometry ,Swedish Mass Spectrometry Society (SMSS)

Track 6: Mass spectrometry configurations and techniques:

Mass Spectrometry Configurations and Techniques is regards to Mass Spectrometry configuration of source, analyzer, and detector becomes conventional in practice, often a compound acronym arises to designate it, and the compound acronym may be better known among nonspectrometrists than the component acronyms. The Mass Spectrometry instrument consists of three major components those are Ion Source: For producing gaseous ions from the substance being studied; Analyzer: For resolving the ions into their characteristics mass components according to their mass-to-charge ratio and Detector System: For detecting the ions and recording the relative abundance of each of the resolved ionic species. A Imaging Mass Spectrometry is simply a device designed to determine the mass of individual atoms or molecules. Atoms of different elements have different masses and thus knowledge of the molecular mass can very often be translated into knowledge of the chemical species involved. TOF MS is the abbreviation for Time of Flight Mass Spectrometry. Charged ions of various sizes are generated on the sample slide and MALDI is the abbreviation for "Matrix Assisted Laser Desorption/Ionization." Mass spectrometry consists basically of weighing ions in the gas phase. The instrument used could be considered as a sophisticated balance which determines with high precision the masses of individual atoms and molecules. Depending on the samples chemical and mechanical propertiess, different ionization techniques can be used. One of the main factor in choosing which ionization technique to be used is biochemical process. For samples that are not themolabile and relatively volatile, ionization such as Electron Impact and/or Chemical Ionization can be effectively used.

Related conferences of mass spectrometry configurations and techniques

2nd International Conference on Current Trends in Mass Spectrometry May 09-11, 2016 Chicago, USA; International Conference and Exhibition on Advances in HPLC and Chromatography Techniques, March 17-18, 2016, London, UK; International Conference on Pharmaceutical Chemistry August 04-06, 2016, Frankfurt, Germany; 4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing, November 02-04, 2015 Atlanta, USA;  2nd International Conference and Expo on Separation Techniques, November 03-05, 2016, Valencia, Spain; Asia Pacific Drug Formulation & Bioavailability Congress June 06-08, 2016, Beijing, China; Global Pharmaceutical Industry Summit September 19-21, 2016, Vienna, Austria; 5th International Conference on Forensic Research & Technology November 17-19, 2016;  International Pharmacy Conference July 11-12, 2016, Philadelphia, USA ;  2nd International Conference on Therapeutic Drug Monitoring and Toxicogenomics, June 09-10, 2016, Dallas, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy

 

64th  ASMS  Conference in Mass spectrometry , June 05-09, 2016; San Antonio, USA ; 21st International Mass Spectrometry  Conference, August 20-26 , 2016, Toronto, Canada BMSS Course: Introduction to  Mass Spectrometry, September 12-13 , 2016, Eastbourne, England , International Summit on Current Trends in Mass Spectrometry May 09-11, 2016, Chicago, USA; Spectroscopy in Pharmaceutical Bioprocessing, April 15-20, 2016 ,  Island, Croatia; MSACL, US-8th Annual conference  & exhibits in Mass spectrometry February 21-25, 2016, Palm springs, California ; Mass Spectrometry Congress November 14-15, 2016, London, UK ; Mass Spectrometry: Applications to the Clinical Laboratory, February21-25, 2016, California, USA; 18th International Conference on Clinical Mass Spectrometry October 27 - 28, 2016, London UK;  Pittcon conference and expo on analytical chemistry and applied spectroscopy , March 6 - 10, 2016, Atlanta, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy,German Mass Spectrometry Society (DGMS),American Society for Mass Spectrometry (ASMS),Swedish Mass Spectrometry Society (SMSS)

Track 8: Ionization techniques

There are many types of ionization techniques are used in mass spectrometry methods. The classic methods that most chemists are familiar with are electron impact (EI) and Fast Atom Bombardment (FAB). These techniques are not used much with modern mass spectrometry except EI for environmental work using GC-MS. Electrospray ionization (ESI) - ESI is the ionization technique that has become the most popular ionization technique. The electrospray is created by putting a high voltage on a flow of liquid at atmospheric pressure, sometimes this is assisted by a concurrent flow of gas. Atmospheric Pressure Chemical Ionization (APCI) - APCI is a method that is typically done using a similar source as ESI, but instead of putting a voltage on the  Electrospray Tandem Mass Spectrometry Newborn Screening itself, the voltage is placed on a needle that creates a corona discharge at atmospheric pressures. Matrix Assisted Laser Electrophoresis is a technique of ionization in which the sample is bombarded with a laser. The sample is typically mixed with a matrix that absorbs the radiation biophysics and transfer a proton to the sample. Gas-Phase Ionization.

Related conferences of ionization techniques

2nd International Conference on Current Trends in Mass Spectrometry May 09-11, 2016 Chicago, USA; International Conference on Pharmaceutical Chemistry August 04-06, 2016 Frankfurt, Germany; 4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing November 02-04, 2015, Atlanta, USA;  2nd International Conference and Expo on Separation Techniques November 03-05, 2016 Valencia, Spain; International Conference and Exhibition on Advances in HPLC and Chromatography Techniques March 17-18, 2016 London, UK; 7th International Conference and Exhibition on Analytical & Bio analytical Techniques September 29-October 01, 2016, Miami, USA; International Conference on Physics, June 27-29, 2016,orleans,USA; 9th World Drug Delivery Summit June 30-July 02, 2016, New Orleans, USA;4th Annual European Pharma Congress July 18-20, 2016 Berlin, Germany; 7th Annual Global Pharma Summit June 20-22, 2016 New Orleans, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy

64th ASMS Conference in Mass spectrometry , June 05-09, 2016; San Antonio, USA 21st International Mass Spectrometry Conference, August 20-26 , 2016, Toronto, Canada; MSACL, US-8th Annual conference  & exhibits in Mass spectrometry February 21-25, 2016, Palm springs, California; BMSS Course: Introduction to  Mass Spectrometry, September 12-13, 2016, Eastbourne, England; 18th International Conference on Clinical Mass Spectrometry October 27-28, 2016, London, UK;  Mass Spectrometry: Applications to the Clinical Laboratory, February21-25, 2016, California, USA Mass Spectrometry Congress November 14-15, 2016, London, UK; Pittcon conference and expo on analytical chemistry and applied spectroscopy , March 6-10, 2016, Atlanta, USA , International Summit on Current Trends in Mass Spectrometry May 09-11, 2016 ,Chicago, USA;  Spectroscopy in Pharmaceutical Bioprocessing, April 15-20, 2016 , Island, Croatia; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy,Taiwan Society for Mass Spectrometry (TSMS)Swedish Mass Spectrometry Society (SMSS)Irish Mass Spectrometry Society (IMSS)

Track 9:chromatography

Chromatography is one of several separation techniques defined as differential migration from a narrow initial zone. Electrophoresis is another member of this group. In this case, the driving force is an electric field, which exerts different forces on solutes of different ionic charge. The resistive force is the viscosity of the non-flowing solvent. The combination of these forces yields ion mobilities peculiar to each solute. Chromatography has numerous applications in biological and chemical fields. It is widely used in biochemical research for the separation and identification of chemical compounds of biological origin.In the petroleum industry the technique is employed to analyze complex mixtures of hydrocarbons.As a separation method, chromatography has a number of advantages over older techniques—crystallization, solvent extraction, and distillation, for example. It is capable of separating all the components of a multicomponent chemical mixture without requiring an extensive foreknowledge of the identity, number, or relative amounts of the substances present. It is versatile in that it can deal with molecular species ranging in size from viruses composed of millions of atoms to the smallest of all molecules—hydrogen—which contains only two; furthermore, it can be used with large or small amounts of material. Some forms of chromatography can detect substances present at the picogram (10−12 gram) level, thus making the method a superb trace analytical technique extensively used in the detection of chlorinated pesticides in biological materials and the environment, in forensic science, and in the detection of both therapeutic and abused drugs. Its resolving power is unequaled among separation methods.

Related conferences of chromatography:

2nd International Conference on Current Trends in Mass Spectrometry May 09-11, 2016 Chicago, USA; International Conference and Exhibition on Advances in HPLC and Chromatography Techniques, March 17-18, 2016, London, UK; International Conference on Pharmaceutical Chemistry August 04-06, 2016, Frankfurt, Germany; 4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing, November 02-04, 2015 Atlanta, USA;  2nd International Conference and Expo on Separation Techniques, November 03-05, 2016, Valencia, Spain; Asia Pacific Drug Formulation & Bioavailability Congress June 06-08, 2016, Beijing, China; Global Pharmaceutical Industry Summit September 19-21, 2016, Vienna, Austria; 5th International Conference on Forensic Research & Technology November 17-19, 2016;  International Pharmacy Conference July 11-12, 2016, Philadelphia, USA ;  2nd International Conference on Therapeutic Drug Monitoring and Toxicogenomics, June 09-10, 2016, Dallas, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy

Spectroscopy in Pharmaceutical Bioprocessing April 15-20, 2016, Island, Croatia ; 21st International Mass Spectrometry Conference  August 20-26, 2016, Toronto, Canada;  BMSS Course: Introduction to  Mass Spectrometry, September 12-13, 2016, Eastbourne, England ; MSACL, US-8th Annual conference  & exhibits in Mass spectrometry , February 21-25, 2016, Palm springs, California ; Mass Spectrometry Congress November 14 - 15, 2016, London, UK ;  18th International Conference on Clinical Mass Spectrometry October 27-28, 2016, London UK ; Mass Spectrometry: Applications to the Clinical Laboratory, February 21-25, 2016, California, USA;  64th  ASMS  Conference in Mass spectrometry ,  June 05-09,2016; San Antonio, USA;  Pittcon conference and expo on analytical chemistry and applied spectroscopy , March 6-10, 2016, Atlanta, USA;  International Summit On Current Trends in Mass Spectrometry, May 09-11, 2016, Chicago, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy,Finnish Mass Spectrometry Society (FMSS),Dutch Society for Mass Spectrometry (NVMS),Taiwan Society for Mass Spectrometry (TSMS)

Track 10: Applications of mass spectrometry

Application of Mass Spectrometry includes the ion and weights separation. The samples are usually introduced through a heated batch inlet, heated direct insertion probe, or a gas chromatograph. Ionization mass spectrometry (ESI-MS) which has become an increasingly important technique in the clinical laboratory for structural study or quantitative measurement of metabolites in a complex biological sample. MS/MS applications are plentiful, for example in elucidation of structure, determination of fragmentation mechanisms, determination of elementary compositions, applications to high-selectivity and high-sensitivity analysis, observation of ion–molecule reactions and thermochemical  data  determination  (kinetic method).Mass spectrometry is an analytical methods with high specificity and a growing presence in laboratory medicine. Various types of mass spectrometers are being used in an increasing number of clinical laboratories around the world, and, as a result, significant improvements in assay performance are occurring rapidly in areas such as toxicology, endocrinology, and biochemical markers. This review serves as a basic introduction to mass spectrometry, its uses, and associated challenges in the clinical laboratory and ends with a brief discussion of newer methods with the greatest potential for Clinical and Diagnostic Research.

Related conferences of applications of mass spectrometry

International Conference on Pharmaceutical Chemistry August 04-06, 2016, Frankfurt, Germany; International Conference and Exhibition on Advances in HPLC and Chromatography Techniques March 17-18, 2016, London, UK; 2nd International Conference on Current Trends in Mass Spectrometry May 09-11, 2016, Chicago, USA; 4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing November 02-04, 2015, Atlanta, USA;  2nd International Conference and Expo on Separation Techniques November 03-05, 2016, Valencia, Spain; 4th Clinical Microbiology and Microbial Genomics Conference October 05-07, 2015 Philadelphia, USA;  pharma Middle East November 02-04, 2015 Dubai, UAE; 8th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems March 07-09, 2016 Madrid, Spain; African Pharma Congress June 20-22, 2016 Cape Town, South Africa; International Pharmacy Conference July 11-12, 2016 Philadelphia, USA; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy

Spectroscopy in Pharmaceutical Bioprocessing April 15-20, 2016, Island, Croatia; BMSS Course: Introduction to  Mass Spectrometry, September 12-13, 2016, Eastbourne, England ; 18th International Conference on Clinical Mass Spectrometry October 27-28, 2016, London UK ; 64th  ASMS  Conference in Mass spectrometry ,  June 05-09, 2016; San Antonio, USA;  MSACL, US-8th Annual conference  & exhibits in Mass spectrometry , February 21 - 25, 2016, Palm springs, California; 21st International Mass Spectrometry  Conference Toronto, Canada, August 20-26, 2016; Pittcon conference and expo on analytical chemistry and applied spectroscopy , March 6-10, 2016, Atlanta, USA,  Mass Spectrometry: Applications to the Clinical Laboratory, February21-25, 2016, California, USA;  International Summit On Current Trends in Mass Spectrometry, May 09-11, 2016, Chicago, USA;  Mass Spectrometry Congress November 14-15, 2016, London, UK; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy,Taiwan Society for Mass Spectrometry (TSMS)Swedish Mass Spectrometry Society (SMSS)Irish Mass Spectrometry Society (IMSS)

Track 11: Liquid chromatography in Mass Spectrometry

Liquid chromatography in mass spectrometry is an analytical chemistry technique that combines the physical separation capabilities of liquid chromatography (or HPLC) with the mass analysis capabilities of mass spectrometry (MS). LC-MS is a powerful technique that has very high sensitivity, making it useful in many applications. Its application is oriented towards the separation, general detection and potential identification of chemicals of particular masses in the presence of other chemicals (i.e., in complex mixtures), e.g., natural products from natural-products extracts, and pure substances from mixtures of chemical intermediates. Preparative LC-MS systems can be used for rapid mass-directed purification of specific substances from such mixtures that are important in basic research, and pharmaceutical, agrochemical, food, and other industries.

Present day liquid chromatography generally utilizes very small particles packed and operating at relatively high pressure, and is referred to as High performance liquid chromatography (HPLC); modern LC-MS methods use HPLC instrumentation, essentially exclusively, for sample introduction. In HPLC, the sample is forced by a liquid at high pressure (the mobile phase) through a column that is packed with a stationary phase generally composed of irregularly or spherically shaped particles chosen or derivatized to accomplish particular types of separations. HPLC methods are historically divided into two different sub-classes based on stationary phases and the corresponding required polarity of the mobile phase. Use of octadecylsilyl (C18) and related organic-modified particles as stationary phase with pure or pH-adjusted water-organic mixtures such as water-acetonitrile and water-methanol are used in techniques termed reversed phase liquid chromatography (RP-LC). Use of materials such as silica gel as stationary phase with neat or mixed organic mixtures are used in techniques termed normal phase liquid chromatography (NP-LC). RP-LC is most often used as the means to introduce samples into the MS, in LC-MS instrumentation

International Conference and Exhibition on Advances in HPLC and Chromatography Techniques March 17-18, 2016, London, UK; 2nd International Conference on Current Trends in Mass Spectrometry May 09-11, 2016 Chicago, USA; International Conference on Pharmaceutical Chemistry August 04-06, 2016, Frankfurt, Germany; 4th International Conference on Medicinal Chemistry & Computer Aided Drug Designing November 02-04, 2015, Atlanta, USA;  2nd International Conference and Expo on Separation Techniques November 03-05, 2016 Valencia,7th Annual Global Pharma Summit June 20-22, 2016, New Orleans, USA; 2nd International Conference and Expo on Bio pharmaceutics September 15-17, 2016, San Antonio, USA; Pharma Middle East November 02-04, 2015 Dubai, UAE;  8th International Conference and Exhibition on Pharmaceutics & Novel Drug Delivery Systems March 07-09, 2016, Madrid, Spain; African Pharma Congress June 20-22, 2016, Cape Town, South Africa; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy

64th ASMS Conference in Mass spectrometry , June 05-09, 2016; San Antonio, USA 21st International Mass Spectrometry Conference, August 20-26 , 2016, Toronto, Canada; MSACL, US-8th Annual conference  & exhibits in Mass spectrometry February 21-25, 2016, Palm springs, California; BMSS Course: Introduction to  Mass Spectrometry, September 12-13, 2016, Eastbourne, England; 18th International Conference on Clinical Mass Spectrometry October 27-28, 2016, London, UK;  Mass Spectrometry: Applications to the Clinical Laboratory, February21-25, 2016, California, USA Mass Spectrometry Congress November 14-15, 2016, London, UK; Pittcon conference and expo on analytical chemistry and applied spectroscopy , March 6-10, 2016, Atlanta, USA , International Summit on Current Trends in Mass Spectrometry May 09-11, 2016 ,Chicago, USA;  Spectroscopy in Pharmaceutical Bioprocessing, April 15-20, 2016 , Island, Croatia; Chemistry Conferences Europe June 16-18, 2016 Rome, Italy, American Society for Mass Spectrometry (ASMS)Belgian Society for Mass Spectrometry  (BSMS), Brazilian Mass Spectrometry Society (BrMASS)

Conferenceseries invites all the participants from all over the world to attend '3rd  International Conference On Mass spectrometry' during  October 10-11, 2016 in Kuala Lumpur, Malaysia, which includes prompt keynote presentations, Oral talks, Poster presentations and Exhibitions.

LCMS-2016  is a unique opportunity to discuss best practices within the laboratory research and those in other industries if the people  are doing related things getting a variety of viewpoints can help us see where we can change or improve our own ideas and processes.There will be many seminars, workshops and technical sessions take place which will catch the attention of the professionals to attend Mass Spectrometry conference and it would enormously enrich our knowledge in understanding the current requirements of the global pharmaceutical industry. The expert will get an excellent opportunity to give many presentations and lectures on different topic and will also present their case studies. 

In the light of this theme, the conference series aims to provide a forum for international researchers from various areas of  mass spectrometry.This conference brings together individuals who are interested in fields of mass spectrometry the Therapeutic approaches for mass spectrometry  paving way to  explore issues of mutual concern as well as exchange knowledge, share evidence and ideas, and generate solutions.As per the Frost and Sullivan report analytical market is growing on an average 0.4%  annually. This report studies the global mass spectrometry market over the forecast period of 2013 to 2018. The market was estimated at $3.9 billion in 2013 and is expected to reach $5.9 billion by 2018, growing at a CAGR of 8.7% from 2013 to 2018.North America dominated the global mass spectrometry market in 2013, followed by Europe and Asia. The North American market is likely to be driven by factors such as the increasing number of government investments in pharmaceutical, biotechnology, medical, and academic research studies that make use of mass spectrometry techniques. On the other hand, Asia is expected to grow at the highest CAGR due to the presence of high-growth markets such as India and China, the improved funding scenario in this region, increasing number of conferences and exhibitions on mass spectrometry, and increased focus of the giant players in these countries.

Conferenceseries Organises 500 +Conferences Every Year across USA, Europe & Asia with support from 1000 more scientific societies and Publishes 700 +Open access Journals which contains over 50000 eminent personalities, reputed scientists as editorial board members.

Target Audience:

·         Directors of analytical chemistry department in Universities

·         Research laboratories Scientist

·         Professor and Associate professor of analytical chemistry

·         Research scholars

·         Analytical instrument manufacturing company

·         Research and Development Department

Target Audience:

Industry        30%

Academia    60%

Others          10%

 

Figure : Target Audience

Top Universities of Mass Spectrometry in USA :

Stanford University

Williams College

Princeton University

Massachusetts Institute of Technology

Princeton University

 

LCMS-2016 welcomes attendees, presenters, and exhibitors from all over the world to Kuala Lumpur, Malaysia . We are delighted to invite you all to attend and register for the “3rd international conference on Mass Spectrometry ' during  October 10-11, 2016 in Kuala Lumpur, Malaysia.

The organizing committee is gearing up for an exciting and informative conference program including plenary lectures, symposia, workshops on a variety of topics, poster presentations and various programs for participants from all over the world. We invite you to join us at the LCMS-2016, where you will be sure to have a meaningful experience with scholars from around the world. All members of the LCMS-2016 organizing committee look forward to meeting you in  Kuala Lumpur, Malaysia.

The mass spectrometry community is probably the largest group of scientists working around a single tool.  Mass spectrometry (MS), arguably the most important analytical spectroscopic tool of modern times.  There is no single area of experimental science where mass spectroscopy is not being used. There is no university or research institution in the developed world without a mass spectrometer.

Why Kuala Lumpur?

The presence of universities, hospitals, legal/accounting and other professional services, together with key installations of the U.S. make it favorite destination for scientific meetings 

The Kuala Lumpur economy is dominated by four major sectors: oil/gas and related activities, tourism, the port and ship/boat building, and aerospace manufacturing. Boasting attractions such as its magnetic French Quarter,  Kuala Lumpur has a history of solid tourist trade. In a city with more than 5 million visitors annually, the hospitality business supplies more than 66,000 jobs in the service sector such as accommodations and restaurants. In 2004, tourists spent $4.9 billion in Kuala Lumpur.

Conference Highlights:

·         Fundamentals of Mass Spectrometry

·         Mass Spectrometry Configuration and Technique

·         Ionization Techniques

·         Application of Mass Spectrometry

·         New Approaches in Mass Spectrometry

·         Experimentation and Data Analysis

·         Maintenance and troubleshooting

·         Mass Spectrometry Imaging

·         Recent Advances in Mass Spectrometry Techniques

          Liquid chromatography in Mass Spectrometry

Why to attend???

1.To learn about key issues in the industry as a whole (and your area of interest in particular) as articulated by practitioners.
2. To meet people and organizations addressing these same key issues.
3. To meet people with whom you’ve established a relationship on social media.
4. To initiate relationships with others that you can continue by social media and/or meetings in person.
5. To learn about job, internship, project and other work-based possibilities.
6. To learn about fellowship and grant opportunities relevant to your area(s) of interest.
7. To gain insight into the experiences of others who face challenges similar to yours.
8. To learn about publications and other resources relevant to your area(s) of interest.

Target Audience:

·         Directors of analytical chemistry department in Universities

·         Research laboratories

·         Professor and Associate professor

·         Research scholar

·         Analytical instrument manufacturing company

·         Research and Development Department

 

Mass Spectrometry-2015

In the presence of inter professional researchers and practitioners involved in the development of high quality education in all aspects of Mass Spectrometry. International Summit on Current Trends in Mass Spectrometry which was held during July 13-15, 2015 in New Orleans, USA

Conferenceseries hosted a diverse panel of key members of the Mass Spectrometry community from academia, research lab, Eminent Scientist, Scholar Students to discuss the theme of the conference “Exhorting and Promulgating Mass Spectrometry and Scientific Research. This event was really aimed to exchange ideas and experience across a variety of topics that cover the latest insights in important aspects of Mass Spectrometry, Mass Spectrometry Configurations and Techniques, New Approaches in Mass Spectrometry, Mass spectrometry Imaging, Applications of Mass Spectrometry, Ionization Techniques, Fundamentals of Mass Spectrometry and  Recent Advances in Mass Spectrometry Techniques.

Mass Spectrometry-2015 Organizing Committee would like to thank the Moderator of the conference and all other attendees who contributed a lot for the smooth functioning of the event

We are also thank full to all the speakers who made this event a grand success, Our Special thanks to Royal Society of Chemistry for collaborating with us and Ionbench for sponsorship at the conference, many thanks to all the media partners for the promotion of our event

International Summit on Current Trends in Mass Spectrometry was a great success with the support of International multi professional steering committee and coordinated by the  Journal of Chromatography & Separation TechniquesJournal of Analytical & Bioanalytical Techniques and Journal of Bioprocessing & Biotechniques. We are happy to announce our 3rd International Conference On Mass Spectrometry' which will be held during  October 10-11, 2016 in Kuala Lumpur, Malaysia

 


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