Biography:

Dr. Khadija Shahid is an Associate Professor at Riphah International University. She is involved in the synthesis of organometallics and their biological activities. She is an expert at using UV-Vis, FT-IR, NMR, Mass Spectrometer HPLC, GC-MS and Atomic Absorption Spectrophotometer. She received her PhD degree in chemistry after completing her 3 years research (Inorganic/analytical) at University of Bayreuth (Germany). She completed a year of Post Doc studies at the same institute. She has served as a Visiting Scientist at University of Bayreuth, Germany. She has published 55+ research papers with 65+ impact factor & citation index of 360 +.

 

Abstract:

Pregabaline (GABA receptor) is an alkylated analogue of inhibitory neurotransmitter γ-amino-butyric acid. Release of several neurotransmitters are substantially reduced by pregabaline. It reduces excessive firing of neurons and hence controls seizers. Potential anticonvulsant activity of pregabaline is the modern antiepileptic drugs that target neuronal voltage-gated sodium, potassium and calcium channels. Pregabaline is used in anxiety disorder. Neither Pregabaline is not used in USA or EU for treating sleep disturbance or enhancing slow-wave sleep. Pregabaline reduces RLS (restless leg syndrome). Imine ligand obtained from different heterocyclic, monocyclic and aliphatic compounds are reported to possess cytotoxic, antiepileptic, anticancer, anti-tubercular, antimalarial, vasorelaxing, neuropathic pain, analgesic and fungicidal activities. Schiff base Reactions have significant role in the synthesis of novel and physiologically reactive compounds. Current research work is an effort to synthesize novel metal complexes of Fe, Zn, Cu and Sn with the imine ligand. The ligand is prepared by reacting 3-(aminomethyl)-5-methyl hexanoic acid with benzaldehyde. Addition of metals to compounds containing imines enhances their biological activity. The structure elucidation is confirmed by FTIR, ¹H NMR and Mass Spectrometry. Agar well diffusion and agar tube dilution methods are used for antibacterial and antifungal screening respectively. Antioxidant scavenging activity is also observed from ligand and their respective metal complexes. MTT calorimetric assay is performed against HeLa cell lines that confirms the anticancer activity of ligand and their metal complexes. The metal complexes exhibited better activity than ligand. The compounds can be screened for more biological activities on further studies.

 

Biography:

Modinah completed her Ph.D. in 2007 from Department of Chemistry, Faculty of Science, University of Ilorin, Nigeria and postdoctoral studies from School of Geography, Earth and Environmental Sciences, University of Birmingham, United Kingdom in 2013. She is the coordinator of GNS 311 of the University. She rose through the ranks and became associate Professor of Chemistry in 2016. She has published more than 25 papers in reputed journals and has been serving as an editorial board member and reviewer of repute. She has supervised and still supervising undergraduate and graduate levels students.      

Abstract:

The study evaluated the chemical composition, physicochemical properties, toxicological and environmental potentials of the Datura metel (D. metel) leaves extracts. Fresh leaves of D. metel were harvested at three different times of the day (morning, afternoon and evening), extraction done in succession using n-hexane and ethanol solvents respectively. Preliminary phytochemical screening, physicochemical analysis for specific gravity, pH, colour, total ash and moisture contents of the dried extracts were determined. The characterisation of the bioactive compounds using Gas Chromatography-Mass Spectrometry, showed the presence of different compounds at three different times of the day, out of which phytol and 9,12,15-octadecatrienoic acid were present at all times. These results confirmed that some bioactive compounds present in this plant are dependent on environmental factor , time of harvest and the choice of solvent used while the presence of others are independent on these factors. Each extract was administered orally to Wistar rats for two weeks. There were significant difference (p < 0.05) in activities of AST (serum and heart), ALT (liver and serum) and ALP (Serum, liver and kidney), as well as the concentrations of albumin and protein in the liver and serum and urea in the serum of experimental rats given n-hexane and ethanolic extracts of D. metel. Generally it also suggest that the leaf extracts collected at three different times of the day had some significant toxicological effect, thus may not be totally safe for consumption at the dosage indicated since tissues membranes integrity of the Wistar rats were not potentially preserved.

 

Biography:

Cynthia Alvarez Garib has a degree in Chemical Engineering from the University of Matanzas, Cuba. She currently works as a teacher in the University of Matanzas in the subjects of General Chemistry and Computer Aided Drawing. She has a great passion for solving technological problems in industries, especially in the alcohol industry, hence the emergence of this research with which she responds to the existing problem.

Abstract:

The present investigation has been carried out in the CubaRon S.A. distillery. In this plant technological changes have been made with respect to the original design. Therefore, in this work, a simulated case study has been carried out to determine the best feed plate in the distillation columns. Through the simulation in HYSYS it has been intended to determine the points where to make the injections in the three distillation columns. The new proposal must guarantee that the alcoholic strength is at least 95.5% v / v.

Biography:

Dhruba babu Subedi is a Physical Chemistry Graduate with a research interest on the material chemistry, corrosion and nano science. He has completed  M. Sc. in Physical Chemistry with first division with dissertation from Tribhuvan University, Kathmandu, Nepal.

He had completed dissertation entitled “STUDY OF THE CORROSION INHIBITION EFFECT ON SPUTTER-DEPOSITED W-xCr-yNi ALLOYS BY NITRITE, MOLYBDATE AND TUNGSTATE IN 0.5 M NaCl.” under the guidance of Prof. Dr. Jagadeesh Bhattarai, my supervisor, for the partial fulfillment of masters degree of science in chemistry.

 

 

Abstract:

Corrosion is a problem of science and technology. It cannot eliminate completely although the corrosion control is becoming more practical and achievable to decrease its rate. Nowadays, the corrosion control method of metals and alloys using various types of eco-friendly coating to save passive film on metal surface is becoming a fundamental academic and research concerns corrosion scientists.

 

All the experiments were conducted under static or dynamic flow conditions at room temperature. The corrosion rate evaluations were implemented by electrochemical measurements (open circuit potential, linear polarization, potentiodynamic polarization, and electrochemical impedance spectroscopy), while surface analytical techniques (SEM/EDS, XRD and XPS) were employed to examine and characterize the compositions, microstructure of alloys and the corrosion product films.