Applications in Mass Spectrometry

Application of Mass Spectrometry includes the ion and weights separation. The samples are usually introduced through a heated batch inlet, heated direct insertion probe, or a gas chromatograph. Ionization mass spectrometry (ESI-MS) which has become an increasingly important technique in the clinical laboratory for structural study or quantitative measurement of metabolites in a complex biological sample. MS/MS applications are plentiful, for example in elucidation of structure, determination of fragmentation mechanisms, determination of elementary compositions, applications to high-selectivity and high-sensitivity analysis, observation of ion–molecule reactions and thermochemical  data  determination  (kinetic  method).

Mass spectrometry is an analytical methods with high specificity and a growing presence in laboratory medicine. Various types of mass spectrometers are being used in an increasing number of clinical laboratories around the world, and, as a result, significant improvements in assay performance are occurring rapidly in areas such as toxicology, endocrinology, and biochemical markers. This review serves as a basic introduction to mass spectrometry, its uses, and associated challenges in the clinical laboratory and ends with a brief discussion of newer methods with the greatest potential for Clinical and Diagnostic Research.

  • Clinical application of mass spectrometry
  • Mass Spectrometry in petroleum, Space Science, astrobiology and atmospheric chemistry
  • Mass spectrometry in the pharmaceutical industry
  • Protein Mass Spectrometry
  • Chromatography Mass Spectrometry
  • Structure Determination of Natural Products by Mass Spectrometry
  • Biomedical applications
  • Mass spectrometry in biology
  • Forensic studies with Mass Spectrometry
  • Ion Mobility Spectrometry

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