Ionization Techniques

There are many varieties of ionization methods are utilized in mass spectrometry methods. The classic methods that most chemists are accustomed to are electron impact (EI) and Fast Atom Bombardment (FAB). These techniques don't seem to be used much with modern mass spectrometry except EI for environmental work using GC-MS. More modern techniques of and other derivative methods have taken their place within the mass spectrometry laboratory. Ionization mass spectrometry which has become an undeniably essential system inside the clinical lab for assisting examination or quantitative estimation of metabolites during a complex natural sample. MS/MS applications are abundant. Mass spectrometry is an investigative strategy with high explicitness and a developing nearness in research center prescription. various kinds of mass spectrometers are being utilized in enormous number of clinical research facilities over the world, and, thus, noteworthy upgrades in test execution are happening quickly in regions like toxicology, endocrinology, and biochemical markers. This review is a fundamental prologue to mass spectrometry.

  • Gas pressure chemical Ionization (APCI)
  • Electrospray ionization (ESI)
  • Matrix-assisted laser desorption ionization (MALDI)

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