10^th Global Summit on Mass Spectrometry August 16-17, 2021 Amsterdam, Netherlands

The primary goal of Bio spectroscopy is to form one forum for molecular spectroscopists performing on biological problems and for bio-researchers who wish to use spectroscopy to advance their research. The principal role of Bio spectroscopy is to produce a singular concentrate on the employment of spectroscopy for understanding more about biological molecules.

• Bio Analysis of materials using Spectrometry.
• Proteomics.
• Genomics.

Mass spectrometry (MS) has evolved to become a powerful analytical tool for both quantitative and qualitative applications, Applications of MS includes the ion and weights separation. The samples are generally introduced through a heated batch inlet, heated direct insertion probe, or gas chromatograph. Ionization (MS) technique has developed to be significant in the field of clinical laboratory for structural study or quantitative measurement of metabolites in a compound biological sample. TANDEM mass spectrometry applications are many, for elucidation of structure, determination of fragmentation mechanisms, determination of elementary compositions, applications to high-selectivity and high-sensitivity analysis, observation of ion–molecule reactions and thermochemical data analysis (kinetic method).

• Recent Advancements in Mass Spectroscopy
• New approaches in Mass Spectrometry utilization
• Errors observed in Mass Spectrometry Equipment and rectifications.

Metabolomics and lipid omics are effective tool that aims to understand metabolites and lipids present in samples of biological origins. Variations in the species or amounts can be used to distinguish phenotypes and biological responses for diseases, genetic modifications, or nutritional and pharmacological treatments. This data lets scientists to understand how an organism works, or to know the underlying mechanism of a disease.

• Mass Spectrometry in analysis of biological products.
• Analysis of protein substances.
• Analysis of  Organic fluids.
• Identification of mutations in cells.

Toxicology is a disciplinary study of poisons, designed to correlate the quantitative and qualitative interactions between poisons and their physiological and behavioral impacts on living system. Some important aspects of toxicology focus on elucidation of the mechanism of action of poison and enhancement of remedies and treatment plans for toxic effects.

• Forensic Science Toxicology


• Industrial Toxicology


• Plant Toxicology


• Food Safety and Toxicology


• Food Chemical Toxicology


• Experimental Toxicologic Pathology


• Toxicogenomics


• Neuro Toxicology


• Advances in Forensic Toxicology Techniques,Advances in Drug Toxicology Testing

Mass spectrometry is widely being applied to study biomolecules and the fastest developing field is the global analysis for identification and quantification of proteins, proteomics. Neuro-proteomics is a complicated method that has a long way to go in terms of profiling the whole neuronal proteome. It’s quite recent field that has many applications in therapy and science.

• Protein Biochemistry and Proteomics
• Proteomics in Computational and Systems Biology
• Plant Proteomics and Applications
• Food and Nutritional Proteomics
• Immunoproteomics and Clinical proteomics
• Protein Engineering and Molecular Design
• Neuroproteomics & Neurometabolomics
• Proteomics Technologies

Liquid chromatography-mass spectrometry analysis of small molecules from biofluids requires sensitive and robust assays. Because of the very complex nature of many biological samples, efficient sample preparation protocols to remove unwanted components and to selectively extract the compounds of interest are an essential part of almost every bioanalytical workflow. High-performance liquid chromatography (HPLC) is a separation technique that can be used for the analysis of organic molecules and ions. HPLC is based on mechanisms of adsorption, partition and ion exchange, depending on the type of stationary phase used. HPLC involves a solid stationary phase, normally packed inside a stainless-steel column, and a liquid mobile phase. Separation of the components of a solution results from the difference in the relative distribution ratios of the solutes between the two phases. HPLC can be used to assess the purity and/or determine the content of many pharmaceutical bioprocessing substances. It can also be used to determine enantiomeric composition, using suitably modified mobile phases or chiral stationary phases. Individual separation mechanisms of adsorption, partition and ion exchange rarely occur in isolation since several principles act to a certain degree simultaneously.In a very environmental monitoring, hydrophilic molecules will tend to associate with each other (like water drops on an oily surface). The hydrophilic molecules in the mobile phase will tend to adsorb to the surface on the inside and outside of a particle if that surface is also hydrophilic. Increasing the polarity of the mobile phase will subsequently decrease the adsorption and ultimately cause the sample molecules to exit the column. This mechanism is called Normal Phase Analytical Chromatography. It is a very powerful technique that often requires non-polar solvents. Due to safety and environmental concerns this mode is used mostly as an analytical technique and not for process applications.

• Developments in Liquid Chromatography and HPLC


• Molecular Exclusion Chromatography


• Ion Exchange Chromatography


• Partition Chromatography


• Instrumentation Principles Involving in Chromatography and HPLC


• Application of High Performance Liquid Chromatography (HPLC)


• Recent Novel Techniques in Chromatography


• Chromatography Industry and Market Analysis


• Separation Techniques in Analytical Chemistry


• Developments in Ion Chromatography


• Developments in Gas Chromatography


• Advances in Various Chromatographic Techniques


• Advances in HPLC and Affinity Chromatography


• HPLC Fingerprinting in Bioinformatics and Computational Biology

Mass spectroscopy is a powerful tool with many applications in pharmaceutical and biomedical field. The increase in sensitivity and resolution of instruments has opened a new dimension in analysis of pharmaceuticals. Mass Spectrosopy is most reliable instrument in pharmaceutical industry, it is used from initial stages of drug development to the final stages of product manufacturing, it is also used to analyse after market product quality.

• Formulation analysis


• Drug evaluation


• Phytochemical analysis


• Structure elucidation


• Peptide and protein sequence/structural analysis

There are many varieties of ionization methods are utilized in mass spectrometry methods. The classic methods that most chemists are accustomed to are electron impact (EI) and Fast Atom Bombardment (FAB). These techniques don't seem to be used much with modern mass spectrometry except EI for environmental work using GC-MS. More modern techniques of and other derivative methods have taken their place within the mass spectrometry laboratory.Ionization mass spectrometry which has become an undeniably essential system inside the clinical lab for assisting examination or quantitative estimation of metabolites during a complex natural sample. MS/MS applications are abundant. Mass spectrometry is an investigative strategy with high explicitness and a developing nearness in research center prescription. various kinds of mass spectrometers are being utilized in enormous number of clinical research facilities over the world, and, thus, noteworthy upgrades in test execution are happening quickly in regions like toxicology, endocrinology, and biochemical markers. This review is a fundamental prologue to mass spectrometry.

• Gas pressure chemical Ionization (APCI),
• Electrospray ionization (ESI),
• Matrix-assisted laser desorption ionization (MALDI),

(NMR)Nuclear Magnetic Resonance spectrometry is an analytical technique applied in quality regulation and research for analysing the content and purity of a sample along with its molecular structure. For example, NMR can quantitatively analyse compounds containing well-known compounds. For unidentified compounds, NMR can either be used to match against spectral libraries or to infer the basic structure directly. Once the elementary structure is known, nuclear magnetic resonance can be used to analyse molecular conformation in solution along with studying physical properties at the molecular level such as conformational exchange, phase changes, solubility, and diffusion. In order to achieve the desired results, different types of NMR techniques are available.

The significance of mass spectrometry (MS) to future of food research is now well established. In last few decades the role of mass spectrometry and related techniques is increasingly developed as an enabling tool in food analysis for quality control. LC-MS coupling have led to the development in new interfaces and extending the possibilities and automation of various procedures. Undoubtedly advances in ionization techniques having a broad range of applicability and high sensitivity for the analysis of high polar and high molecular mass compounds of food concern have been the key of this development in last few years.

• Analysis of  food poisioning.
• Analysis of  packaged food contents.
• Analyis of  food nutrition.

The novelty is to use mass spectrometry to switch radiolabeling and radioactivity measurements, which represent up-to-now the gold standard to live chemical compound concentrations in bioscience. The capacity of ICP-MS to produce high-resolution quantitation of metallic and hetero elements. In contrast to molecular mass spectrometry that produces ions from entire organic entities, elemental mass spectrometry, referred to as inductively coupled plasma-mass spectrometry (ICP-MS), operates at very high temperatures (up to 8000 K) allowing to interrupt all chemical bonds.

• Analysis of metals.
• Quality checking of metals.
• Analysis of geological materials.