Scientific Program

Conference Series Ltd invites all the participants across the globe to attend International Summit on Current Trends in Mass Spectrometry New Orleans, USA.

Day 1 :

Conference Series Mass Spectrometry-2015 International Conference Keynote Speaker Marek M. Kowalczuk photo
Biography:

Marek M Kowalczuk received his PhD degree in 1984 from the Faculty of Chemistry, Silesian University of Technology, and DSc degree in 1994 at the same University. He was a visiting Lecturer at the University of Massachusetts in Amherst, MA, USA in 1990 and Marie Curie EU fellow at the University of Bologna, Italy. Currently, he is Professor at the University of Wolverhampton, UK at the Centre of Polymer and Carbon Materials, Polish Academy of Sciences, Zabrze, Poland. He is the author and co-author of over 120 scientific papers and a score of patents. His research interests are novel mass spectrometry techniques for analysis of polymers at the molecular level, mechanisms of anionic polymerization related to the synthesis of biodegradable polymers possessing desired architecture, forensic engineering of biodegradable and functional polymers.

Abstract:

Mass spectrometry becomes nowadays a comprehensive analytical technique for copolymer characterization. Copolymers can exist in variety of co-monomer arrangements along the macromolecular chain such as block, gradient, random or alternating copolymers. Moreover, in addition to molecular mass distribution (MMD) the copolymers exhibit co-monomer composition distribution (CCD) and both these factors influence their physical properties for a given copolymer chemical composition. The aims of this study were focused on ESI tandem mass spectrometry of natural aliphatic copolyesters (PHA) and novel sequence-controlled copolymers obtained by anionic ring opening copolymerization of β-substituted β-lactones. Detailed analysis of these copolymers, including molecular chain architecture as well as chemical structure of the end groups, were established based on the ESI-MS/MS collision induced dissociation spectra. The arrangement of co-monomer structural units along the copolyester chains was demonstrated by comparison of the ESI-MS/MS fragmentation spectra and the respective fragmentation pathways. Moreover, the sequence distribution analysis of co-monomeric units confirmed the desired structure of novel sequence-controlled macromolecules. Understanding of the formation mechanisms of sequence-controlled copolymers and a detailed description of the individual reactions taking place at the initiation, propagation and termination of the copolymer chain growth are essential from standpoint of the relations between copolymer structure, properties and function. Thus, the ESI-MS/MS proved to be a favorable technique for structural analysis of the natural and synthetic biodegradable macromolecules.

Keynote Forum

Roger P Webb

University of Surrey, UK

Keynote: Ambient pressure mass spectrometry of fingerprints

Time : 9:30 - 10:00 AM

Conference Series Mass Spectrometry-2015 International Conference Keynote Speaker Roger P Webb photo
Biography:

Roger P Webb completed his PhD from Salford University and performed Postdoctoral studies at the Naval Postgraduate School in Monterey, Ca, USA. He is now the Director of the Surrey Ion Beam Centre, the National Centre for Ion Beam Applications in the UK. He has published more than 250 papers in reputed journals and has served on editorial boards of a number of journals and is a member of the scientific program committees of a number of international conferences.

Abstract:

Ambient pressure mass spectrometry of latent fingerprints provides a potential route to the secure, high throughput and non-invasive detection of, amongst other things, drugs of abuse. We have shown that it is possible to detect both the drugs of abuse as well as the excreted metabolites in the fingerprints using ambient mass spectrometry. A recent press release on this work reported in the Analyst received a large amount of media interest around the world. We report here on the preliminary study employing MALDI, SIMS, DESI and paper spray backed up by GC-MS of oral fluids. The study shows that ambient mass spectrometry can detect cocaine, benziylecgonine (BZE) and methylecgonine (EME) in the fingerprints of drug users. The results provide exciting opportunities for the use of fingerprints a new sampling medium for secure, non-invasive drug detection. The mass spectrometry techniques used offer a high level of selectivity and consume only a small area of a single fingerprint, allowing repeat and high throughput analyses of a single sample.